KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SOCS7
All Species:
23.64
Human Site:
S435
Identified Species:
43.33
UniProt:
O14512
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14512
NP_055413.1
581
62969
S435
S
D
P
R
Y
I
L
S
L
S
F
R
S
Q
G
Chimpanzee
Pan troglodytes
XP_512211
535
59559
E375
V
V
T
S
L
T
E
E
L
K
K
L
A
K
Q
Rhesus Macaque
Macaca mulatta
XP_001082440
360
39867
R229
P
D
G
S
F
L
V
R
D
S
S
D
P
R
Y
Dog
Lupus familis
XP_548159
411
45633
M279
G
I
T
H
H
T
R
M
E
H
Y
R
G
T
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8VHQ2
579
62765
S433
S
D
P
R
Y
I
L
S
L
S
F
R
S
Q
G
Rat
Rattus norvegicus
XP_001081372
564
60962
S418
S
D
P
R
Y
I
L
S
L
S
F
R
S
Q
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506079
518
56852
P371
R
Q
G
W
Y
W
G
P
I
T
R
W
E
A
E
Chicken
Gallus gallus
XP_423895
264
29931
E133
P
M
N
W
E
D
A
E
M
K
L
K
G
K
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_684929
733
79803
S587
S
D
P
R
Y
I
L
S
L
S
F
R
S
Q
G
Tiger Blowfish
Takifugu rubipres
NP_001116335
565
61771
S419
S
D
P
R
Y
I
L
S
L
S
F
R
S
Q
G
Fruit Fly
Dros. melanogaster
NP_523390
1016
110741
S880
S
D
D
H
Y
I
F
S
L
S
F
K
L
N
N
Honey Bee
Apis mellifera
XP_397211
804
90105
S655
S
D
D
H
Y
I
F
S
L
S
F
R
L
N
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792866
847
94386
E456
R
N
D
E
S
F
K
E
N
S
M
Y
G
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.6
43
69.5
N.A.
97.4
95.1
N.A.
24.1
42.6
N.A.
38.2
52.3
22
24.8
N.A.
27.8
Protein Similarity:
100
36.8
49.5
69.7
N.A.
98.1
95.8
N.A.
34.4
43.7
N.A.
48.2
62.4
32.1
39.2
N.A.
39
P-Site Identity:
100
6.6
13.3
6.6
N.A.
100
100
N.A.
6.6
0
N.A.
100
100
53.3
60
N.A.
6.6
P-Site Similarity:
100
20
40
20
N.A.
100
100
N.A.
20
20
N.A.
100
100
60
60
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
62
24
0
0
8
0
0
8
0
0
8
0
0
0
% D
% Glu:
0
0
0
8
8
0
8
24
8
0
0
0
8
0
8
% E
% Phe:
0
0
0
0
8
8
16
0
0
0
54
0
0
0
8
% F
% Gly:
8
0
16
0
0
0
8
0
0
0
0
0
24
0
39
% G
% His:
0
0
0
24
8
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
54
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
0
16
8
16
0
16
0
% K
% Leu:
0
0
0
0
8
8
39
0
62
0
8
8
16
0
0
% L
% Met:
0
8
0
0
0
0
0
8
8
0
8
0
0
0
0
% M
% Asn:
0
8
8
0
0
0
0
0
8
0
0
0
0
16
8
% N
% Pro:
16
0
39
0
0
0
0
8
0
0
0
0
8
8
8
% P
% Gln:
0
8
0
0
0
0
0
0
0
0
0
0
0
39
8
% Q
% Arg:
16
0
0
39
0
0
8
8
0
0
8
54
0
8
0
% R
% Ser:
54
0
0
16
8
0
0
54
0
70
8
0
39
0
8
% S
% Thr:
0
0
16
0
0
16
0
0
0
8
0
0
0
8
0
% T
% Val:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
16
0
8
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
62
0
0
0
0
0
8
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _